"BIO"A little bit of general information!
I'm Sasha and I'm a
Hi! My name is Aleksandra A. Zagulyaeva.
I am a Postdoctoral Fellow at Novartis Institutes for Biomedical Research (NIBR) in Cambridge, MA. Before joining NIBR, I received my undergraduate degree in Organic Chemistry from M.V. Lomonosov Moscow State University, my Masters in Organic Chemistry from the University of Minnesota Duluth, and my doctoral degree in Chemical Biology from the University of Florida. My doctoral research was aimed at elucidating the mechanism of action of MbtH-like protein (MLP), an integral component of many bacterial NRPS systems producing pharmaceutically valuable bioactive compounds. Understanding how MLPs work has important implications for developing antimicrobial therapies as well as for the production of novel molecular scaffolds for medicinal applications.
I have experience in multiple areas of chemistry, ranging from multistep synthesis of target compounds to crystallization and structure determination of protein complexes. At NIBR, I am working in biosystems engineering and aim to further antimicrobial research in the future.
PublicationsAn aggregation of my scientific publications
2.11 - Structural Biology of Nonribosomal Peptide Synthetases
A General and Convenient Preparation of [Bis(trifluoroacetoxy)iodo]perfluoroalkanes and
[Bis(trifluoroacetoxy)iodo]arenes by Oxidation of Organic Iodides Using Oxone and
Hofmann Rearrangement of Carboxamides Mediated by Hypervalent Iodine Species Generated in
Situ from Iodobenzene and Oxone: Reaction Scope and Limitations
A European Journal
Iodine(V)/Ruthenium(III)‐Cocatalyzed Oxidations: A Highly Efficient Tandem Catalytic
System for the Oxidation of Alcohols and Hydrocarbons with Oxone
Journal of Organic Chemistry
1,3-Dipolar Cycloaddition of Schiff Bases and Electron-Deficient Alkenes Catalyzed by
I’m currently working towards my next publication!